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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DKK1
All Species:
9.09
Human Site:
Y132
Identified Species:
28.57
UniProt:
O94907
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94907
NP_036374.1
266
28672
Y132
A
M
C
C
P
G
N
Y
C
K
N
G
I
C
V
Chimpanzee
Pan troglodytes
XP_507795
266
28649
Y132
A
M
C
C
P
G
N
Y
C
K
N
G
I
C
V
Rhesus Macaque
Macaca mulatta
XP_001098844
266
28548
Y132
A
M
C
C
P
G
N
Y
C
K
N
G
I
C
V
Dog
Lupus familis
XP_851978
241
26516
C107
M
C
C
P
G
N
Y
C
K
N
G
I
C
M
P
Cat
Felis silvestris
Mouse
Mus musculus
O54908
272
29250
N138
C
P
G
N
Y
C
K
N
G
I
C
M
P
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505285
429
45606
C295
M
C
C
P
G
N
V
C
S
N
G
I
C
V
P
Chicken
Gallus gallus
XP_421563
338
35145
L205
R
R
R
R
K
R
C
L
R
D
A
M
C
C
P
Frog
Xenopus laevis
NP_001079061
259
28846
I124
G
N
Y
C
S
N
G
I
C
V
P
V
E
Q
D
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.7
69.1
N.A.
80.5
N.A.
N.A.
42.4
42.5
56
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.2
72.9
N.A.
86.4
N.A.
N.A.
48.4
53.5
66.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
0
N.A.
N.A.
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
0
N.A.
N.A.
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
38
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
13
25
63
50
0
13
13
25
50
0
13
0
38
50
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
25
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
13
0
25
38
13
0
13
0
25
38
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
13
0
25
38
0
0
% I
% Lys:
0
0
0
0
13
0
13
0
13
38
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% L
% Met:
25
38
0
0
0
0
0
0
0
0
0
25
0
13
0
% M
% Asn:
0
13
0
13
0
38
38
13
0
25
38
0
0
0
0
% N
% Pro:
0
13
0
25
38
0
0
0
0
0
13
0
13
0
38
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
13
13
13
13
0
13
0
0
13
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
0
13
0
0
0
0
13
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
13
0
0
13
0
13
0
13
38
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
13
0
13
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _